Following, the two cell types are separately combined with hydrogels to form bioinks for the parenchymal cardiac tissue and blood vessels. While the cells are reprogrammed to become pluripotent stem cells, and differentiated to cardiomyocytes and endothelial cells, the extracellular matrix is processed into a personalized hydrogel. To this end, a biopsy of an omental tissue is taken from patients. Here, a simple approach to 3D-print thick, vascularized, and perfusable cardiac patches that completely match the immunological, cellular, biochemical, and anatomical properties of the patient is reported. The advantage of the program is its versatility and applicability in a wide variety of industries and science.Generation of thick vascularized tissues that fully match the patient still remains an unmet challenge in cardiac tissue engineering. A set of additional modules (AC / DC Module, Chemical Engineering Module, Earth Science Module, Heat Transfer Module, etc.) provides an accelerated solution to specific problems. Professionals are offered advanced tools for post-processing, visualization of models and sharing of analysis results. made while working in COMSOL or Autodesk Inventor will be automatically accepted by both applications.
With this interface, any changes made while working in COMSOL or Autodesk Inventor will be automatically adopted in both applications. To better integrate COMSOL Multiphysics with third-party design systems, support for Parasolid files has been added and a new interface has been added for two-way interaction with Autodesk Inventor. In the so-called physical mode of operation, it is also possible to use predetermined equations for most of the phenomena that occur in science and technology, such as the transfer of heat and electricity, the theory of elasticity, diffusion, wave propagation and fluid flow. Of course, in any case, a system of equations will be solved, and the difference lies only in the ability to use physical systems of units and physical terminology. It allows you to solve problems from the field of electromagnetism, the theory of elasticity, the dynamics of liquids and gases, and chemical gas dynamics.ĬOMSOL Multiphysics also makes it possible to solve the problem both in a mathematical formulation (in the form of a system of equations) and in a physical one (selection of a physical model, for example, a model of the diffusion process). COMSOL Multiphysics (Femlab) is a simulation package that solves systems of nonlinear partial differential equations using the finite element method in one, two, and three dimensions.